What Are Inflammatory Mediators? Defining Inflammatory Mediators
What are inflammatory mediators?
Inflammatory mediators are substances produced by cells in response to injury or infection. They cause inflammation, which is the body's way of defending itself against harmful stimuli.
What are examples of inflammatory mediators?
Examples of inflammatory mediators include cytokines, chemokines, histamine, prostaglandins, and leukotrienes. These substances can cause redness, swelling, pain, and heat in the affected area.
How do inflammatory mediators work?
Inflammatory mediators work by causing the blood vessels to dilate, which increases blood flow to the affected area. This leads to redness and warmth. They also increase the permeability of the blood vessels, allowing white blood cells to enter the area and fight off infection.
Why are inflammatory mediators important?
Inflammatory mediators are important because they play a crucial role in the body's immune response. They help to protect the body from infection and injury. However, excessive inflammation can also be harmful and lead to chronic diseases.
What conditions are associated with excessive inflammatory mediators?
Excessive inflammatory mediators are associated with many chronic conditions, including arthritis, asthma, diabetes, heart disease, and cancer.
How are inflammatory mediators involved in allergic reactions?
Inflammatory mediators play a key role in allergic reactions by causing the release of histamine and other chemicals that trigger allergy symptoms, such as itching, swelling, and difficulty breathing.
Can certain foods trigger the release of inflammatory mediators in people with allergies?
Yes, certain foods can trigger the release of inflammatory mediators in people with allergies. For example, some people with food allergies may experience anaphylaxis, a severe and potentially life-threatening allergic reaction that involves the release of inflammatory mediators.
Are there medications that can block the effects of inflammatory mediators in people with allergies?
Yes, there are medications, such as antihistamines and corticosteroids, that can block the effects of inflammatory mediators in people with allergies. These medications can help to reduce allergy symptoms, such as itching and swelling.
Can exposure to environmental pollutants increase the production of inflammatory mediators in people with allergies?
Yes, exposure to environmental pollutants, such as air pollution and cigarette smoke, can increase the production of inflammatory mediators in people with allergies. This can make allergy symptoms worse and increase the risk of developing chronic respiratory conditions.
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