What Is Immunoglobulin G (IgG)? Defining Immunoglobulin G (IgG)
What is immunoglobulin G?
Immunoglobulin G (IgG) is a type of antibody that plays a crucial role in the immune system by recognizing and binding to specific antigens, such as bacteria and viruses.
How does IgG differ from other immunoglobulins?
IgG is the most abundant immunoglobulin in the blood and can cross the placenta from mother to fetus. It also has a longer half-life than other immunoglobulins, meaning it remains in the bloodstream for a longer period of time.
What are the functions of IgG?
IgG has several functions, including neutralizing toxins and viruses, opsonization (marking of foreign cells for destruction by immune cells), and activating the complement system to help destroy foreign cells.
What are the clinical applications of IgG?
IgG testing can be used to diagnose allergies, autoimmune disorders, and infections such as hepatitis B and C. It can also be used to monitor response to vaccination and to treat certain conditions, such as immune deficiencies and autoimmune diseases.
What is the role of IgG in allergic reactions?
IgG antibodies can be involved in both allergic and non-allergic reactions. They can bind to allergens and trigger the release of histamine and other chemicals, leading to allergic symptoms.
Can IgG testing be used to diagnose allergies?
IgG testing is controversial in the diagnosis of allergies. It is not considered a reliable test by many allergists and immunologists, as high levels of IgG antibodies can be found in both allergic and non-allergic individuals.
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